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. 2025 Dec 15;12(1):9. doi: 10.1038/s41537-025-00712-z

Table 1.

Four clusters based on semantic embeddings with TLC as backbone.

Description Scale index Rating-scale items according to TLC-clustering
Group 1 features result in muddled communication with some incomprehensible elements. Meaning distortion, word substitution, and weak context association occur. The absence of crucial “cementing words” worsens confusion, causing difficulties in word sequencing. TLI-6 Peculiar sentences
TLI-5 Peculiar use of words
TLC-7 Incoherence (Word salad, Jargon Aphasia)
TLC-20 Semantic paraphasia
TLC-19 Phonemic paraphasia
TLC-11 Word approximations (Paraphasia, Metonyms)
TLC-10 Neologisms
TALD-4 Dissociation of thinking (Incoherence/Distraction)
TALD-21 Concretism
TALD-14 Neologisms
TALD-13 Phonemic paraphasia
TALD-12 Semantic paraphasia
SAPS-SANS-28 Incoherence
CLANG-6 Discourse failure (Loss of schematic organization)
CLANG-5 Referential failures
CLANG-2 Abnormal syntax
CLANG-17 Paraphasic error
CLANG-16 Neologisms
CLANG-13 Dysarthria
BIT-6 Confused or disorganized ideas.
BIT-1 Strange verbalizations
Group 2 features involve abrupt topic shifts in response to stimuli, repeated words or subjects, speech interruptions, and memory lapses regarding previous speech. TLI-3 Perseveration of ideas
TLC-9 Clanging
TLC-4 Distractible speech
TLC-3 Pressure of speech
TLC-18 Self-reference
TLC-16 Blocking
TLC-14 Perseveration
TALD-9 Pressured speech
TALD-7 Verbigeration
TALD-5 Crosstalk
TALD-30 Pressure/Rush of thoughts
TALD-29 Thought interference
TALD-27 Expressive speech dysfunction
TALD-26 Receptive speech dysfunction
TALD-25 Inhibited thinking
TALD-24 Poverty of thought
TALD-23 Rumination
TALD-22 Blocking
TALD-19 Slowed thinking
TALD-18 Restricted thinking (o)
TALD-15 Clanging
TALD-10 Logorrhoea
SAPS-SANS-33 Clanging
SAPS-SANS-32 Distractible speech
SAPS-SANS-31 Pressure of speech
SAPS-SANS-23 Social inattentiveness
SAPS-SANS-11 Blocking
PANSS-N7 Stereotyped thinking
PANSS-N6 lack of spontaneity and flow of conversation
CLANG-4 Lack of semantic association
CLANG-15 Pressure of speech
CLANG-14 Poverty of speech
CLANG-12 Dysfluency
CLANG-10 Abnormal prosody
CLANG-1 Excess phonetic association
BIT-11 Strange behaviour
Group 3 features include unfounded conclusions, irrelevant replies, a lack of thought continuity, off-topic wandering, disjointed ideas, and a dearth of meaningful connections, resulting in inconsistent narrative structure. TLI-7 Non-logical reasoning (peculiar logic)
TLI-4 Looseness
TLI-2 Weakening of goal
TLC-8 Illogicality
TLC-6 Derailment/Loose association/Flight of ideas
TLC-5 Tangentiality
TLC-13 Loss of goal
TALD-8 Rupture of thought
TALD-6 Perseveration
TALD-3 Tangentiality
TALD-28 Dysfunction of thought initiative and Intentionality
TALD-2 Derailment
SAPS-SANS-29 Illogicality
SAPS-SANS-27 Tangentiality
SAPS-SANS-26 Derailment
SAPS-SANS-12 Increased response latency
PANSS-P2 Conceptual disorganization
PANSS-N5 Difficulty in abstract thinking
CLANG-8 Lack of details (in given context)
CLANG-7 Excess level details (in given context)
CLANG-11 Pragmatics disorder
BIT-9 Attending to a part of rather than the whole question
BIT-8 Intermingling of personal concerns/associations into the response.
BIT-7 Overelaborated response.
BIT-5 Peculiar or idiosyncratic reasoning or logic.
BIT-4 Responses that are deviant with respect to social convention.
BIT-3 Responses involving coherent but odd ideas
BIT-10 Lack of a relationship between subject’s statement and question asked
Group 4 features entail restricted speech, brief concrete answers, omission of additional information, overly concise replies, uninformative or indirect responses with vague, repetitive, or abstract language, hindering meaningful information extraction by interviewers. TLI-1 Poverty of speech
TLC-2 Poverty of content of Speech
TLC-17 Stilted speech
TLC-15 Echolalia
TLC-12 Circumstantiality
TLC-1 Poverty of speech
TALD-20 Poverty of speech (o)
TALD-17 Poverty of content of speech
TALD-16 Echolalia
TALD-11 Manneristic speech
TALD-1 Circumstantiality
SAPS-SANS-9 Poverty of speech
SAPS-SANS-30 Circumstantiality
SAPS-SANS-10 Poverty of speech content
CLANG-9 Aprosodic speech
CLANG-3 Excess syntactic constraints (Excess grammar)
BIT-2 Lack of shared communication.

Descriptions of clusters were generated by LP and used for clinical rater agreement; for a visual representation of clusters, see Fig. 3 and supplemental Fig. 1.