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. 2025 Dec 12;6:41. doi: 10.1038/s43856-025-01298-4

Fig. 3. Distribution of breast cancer polygenic risk scores (PRS313, build GRCh38), allowing the number of variants used to differ with array/ lc-WGS, using the maximum number of variants with R-squared (Rsq) greater than threshold.

Fig. 3

The reference mean value of 0.130 (based on the PRS313 distribution in non-breast cancer controls of a previously published dataset) and the 80th percentile with the corresponding score of ~0.6 are indicated.