TABLE 2.
Anti-FHA and anti-PT IgG titers in sera of i.n. immunized micea
| Immunization | Anti-FHA IgG titer | Anti-PT IgG titer |
|---|---|---|
| B. pertussis | ||
| BPSM | 1.6 × 104 | NDb |
| BPSA87 | <10 | ND |
| BPSA90 | <10 | ND |
| Antigens | ||
| FHA | 3.6 × 105 | <10 |
| Fha44 | 3.1 × 104 | <10 |
| PT | <10 | 4.1 × 105 |
| FHA + PT | 1.7 × 106 | 7.3 × 105 |
| Fha44 + PT | 2.5 × 105 | 6.5 × 105 |
| PBS | <10 | <10 |
For B. pertussis-infected mice, serum samples were collected and pooled from eight mice per group 8 weeks after infection. For mice immunized with purified antigens, serum samples were collected and pooled from 10 mice per group 2 weeks after the last immunization.
ND, not determined.