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. 2026 Jan 6;15:1711701. doi: 10.3389/fonc.2025.1711701

Table 4.

Univariate and multivariate analysis of factors influencing hemostatic effectiveness.

Variables Univariate OR (95% CI) P-value Multivariate OR (95% CI) P-value
Age (years)
 <48 Reference
 ≥48 1.335 (0.768-2.323) 0.306
FIGO stage
 ≤IIB Reference Reference
 ≥IIIA 0.443 (0.228-0.864) 0.017 0.333 (0.157-0.708) 0.004
Tissue differentiation
 Well differentiated Reference
 Moderately differentiated 1.128 (0.521-2.441) 0.760
 Poorly differentiated 0.750 (0.323-1.741) 0.504
Tumor location
 outward Reference
 Inward 0.679 (0.351-1.313) 0.250
 Mixed 0.932 (0.465-1.867) 0.843
Pathological type
 Squamous cell carcinoma Reference
 Adenocarcinoma or Adenosquamous carcinoma 1.151 (0.500-2.648) 0.741
Maximum tumor diameter (cm) 0.997 (0.850-1.169) 0.969
HPV infection status
 HPV16 Reference
 HPV18 1.053 (0.460-2.412) 0.902
 Other types 1.024 (0.551-1.905) 0.939
Hematological parameters
 HB (g/L) 0.994 (0.981-1.007) 0.340
 RBC (x10^12/L) 0.934 (0.629-1.386) 0.733
 HCT (%) 0.981 (0.938-1.026) 0.398
 PLT (x10^9/L) 0.998 (0.996-1.001) 0.149 0.999 (0.996-1.001) 0.298
Liver function
 ALT (IU/L) 0.986 (0.969-1.002) 0.093 0.989 (0.969-1.008) 0.256
 AST (IU/L) 0.995 (0.974-1.015) 0.604
 ALB (g/L) 0.964 (0.908-1.024) 0.231
 TBil (μmol/L) 1.033 (0.963-1.108) 0.365
Coagulation function
 PT (s) 1.123 (0.840-1.500) 0.434
 APTT (s) 1.004 (0.930-1.083) 0.924
 TT (s) 1.053 (0.915-1.211) 0.472
 FIB (g/L) 1.000 (0.744-1.342) 0.998
Blood loss volume (ml/d)
 100-200 Reference Reference
 >200 0.631 (0.362-1.099) 0.104 0.551 (0.283-1.073) 0.079
Transfusion status
 No Reference Reference
 Yes 0.664 (0.377-1.172) 0.158 0.570 (0.281-1.157) 0.119
Urinary system obstruction
 No Reference
 Yes 0.901 (0.472-1.719) 0.751
Treatment method
 VP Reference Reference
 PAE 11.449 (5.379-24.370) <0.001 14.026 (6.343-31.015) <0.001