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Colonization capacity of H. influenzae and isogenic htrB mutants
| Strain | htrB | Colonization of human respiratory xenograftsa
|
||
|---|---|---|---|---|
| Type | Inoculum | No. colonized/total no. | ||
| E1a | + | b | 103 | 10/10 |
| E1a∗ | − | b | 103 | 1/10 |
| R3001 | + | NTHi | 102 | 10/10 |
| R3001a | − | NTHi | 102 | 2/10 |
| 2019 | + | NTHi | 103 | 10/10 |
| B29 | − | NTHi | 103 | 0/10 |
Colonization is defined as present if the xenograft flush or homogenate culture yielded H. influenzae 5 days (flush) or 7 days (homogenate) after inoculation.
