TABLE 1.
Effect of F-A2M on trypomastigotes of T. Cruzi
| Concn of F-A2M (μg/ml) in: | Trypomastigote characteristicsa
|
|||
|---|---|---|---|---|
| Morphology
|
Motilityb
|
|||
| 5 h | 24 h | 5 h | 24 h | |
| Blood | ||||
| 0 | Slender | Slender | 3 | 3 |
| 1 | Slender | Slender | 3 | 3 |
| 10 | Slender | Slender | 3 | 3 |
| 25 | Stout | Stout | 2 | 2 |
| 50 | Stout | Round | 2 | 2 |
| 100 | Stout | Round | 2 | 1 |
| Culture | ||||
| 0 | Slender | Slender | 3 | 2 |
| 1 | Stout | Stout | 3 | 2 |
| 10 | Stout | Stout | 3 | 2 |
| 25 | Round | Round | 2 | 1 |
| 50 | Round | Round | 1 | 0 |
| 100 | Round | Lysed | 1 | —c |
a
T. cruzi Y strain.
b
Classification ranges from 0 to 3 to score the motility of parasites: 0 = immobile; 3 = highly mobile. Results shown are the means of four independent experiments.
c
—, impossible to evaluate.