Table 1.

Clinical features of six patients with renal deterioration on combined therapy with ACE/NSAID

Age	Risk factors	Baseline creatinine (μmol/L)	Peak creatinine (μmol/L)	Drug added	Drug stopped
81	Diuretics;			NSAID	Both
	malignancy	101	429
85	Diuretics;			NSAID	Both
	diarrhoea	58	403
88	Diuretics	58	124	NSAID	NSAID
89	Diuretics	72	157	ACEI	ACEI
79	Diuretics	95	158	ACEI	NSAID
78	Diuretics	86	146	ACEI	NSAID
ACEI=Angiotensin converting enzyme inhibitor; NSAID=nonsteroidal anti-inflammatory drug