TABLE 4.
Effects of Lf411 mutants on the adherence of S. mutans MT8148 cells to S-HA beads
| Mutant Lf411 | No. of cells bound to S-HA (106)a | % Inhibitionb |
|---|---|---|
| Control | 5.26 ± 0.36 | |
| Lf411 | 4.26 ± 0.06c | 19.0 |
| Lf411-C481S | 1.65 ± 0.25d | 68.6 |
| Lf411-C491S | 4.63 ± 0.43 | 15.8 |
| Lf411-C502S | 4.51 ± 0.61 | 14.3 |
| Lf411-C505S | 4.89 ± 0.63 | 7.0 |
| Lf411-C515S | 4.71 ± 0.14 | 10.5 |
| Lf411-C532S | 1.92 ± 0.13d | 63.5 |
a
The values were obtained at 1.0 nmol of mutant Lf411/ml, and are expressed as the means ± standard deviations of triplicate assays.
b
Percent inhibition was calculated as described in Table 1.
c
P < 0.05 compared with control.
d
P < 0.001 compared with control.