Skip to main content
. Author manuscript; available in PMC: 2005 Nov 10.
Published in final edited form as: Nat Immunol. 2005 May 15;6(6):579–586. doi: 10.1038/ni1204

Figure 4.

Figure 4

Syk-deficient macrophages secrete increased amounts of proinflammatory cytokines in response to TLR stimulation. Bone marrow-derived macrophages from wild-type mice, DAP12-deficient (DAP12 KO) mice or Syk-deficient (Syk KO) fetal liver chimeras were incubated with the indicated concentrations of LPS, CpG DNA, or synthetic bacterial lipopeptide for 16 h. Supernatants were collected and the amounts of TNF (a), IL-6 (b) and IL-12 p40 (c) were measured using ELISA. Data are representative of three independent experiments.