TABLE 1.
Body weights, antibody titers, and lipid profiles of C57BL/6J mice inoculated with C. pneumoniae in comparison to control mice
Group (no. of weeks after first inoculation)a | Infection | Body weight (g [mean ± SD]) | Antibody titer (range) | Cholesterol (mg/dl [mean ± SD]) | Triglycerides (mg/dl [mean ± SD]) |
---|---|---|---|---|---|
Group 1 (5 weeks) | Yes (n = 15) | 31.7 ± 2.7 | 1:128-1:1024 | 140.9 ± 34.7 | 49.0 ± 12.9 |
No (n = 13) | 30.6 ± 1.5 | Negative | 157.3 ± 25.3 | 45.6 ± 21.6 | |
Group 2 (7 weeks) | Yes (n = 14) | 30.3 ± 1.3 | 1:64-1:512 | 158.4 ± 21.5 | 46.5 ± 15.6 |
No (n = 15) | 30.8 ± 1.4 | Negative | 165.2 ± 33.7 | 37.5 ± 11.4 |
For each group, the number of weeks is the time after the first inoculation that the atherogenic diet was begun.