Fig. 2.

Plot of the oesophageal multivariable models with and without concurrent chemotherapy. The orange line is the fitted regression model with chemotherapy, the light blue line is the fitted regression model without chemotherapy, the red dotted line indicates the 20% toxicity level. The dots represent the toxicity rate from each paper (labelled), with the size of the dots proportional to the number of patients in the study, vertical bars are the 68% binomial confidence interval, horizontal bars represent the range of the doses. The chemotherapy rate for each study is represented on a blue/red scale, with red indicating 100% rate of concurrent chemotherapy, and blue representing a 0% rate. Due to overlapping data points, the scatter plot has been jittered.