Table 3.
Summary of multivariable model dose predictions with and without chemotherapy. CI: confidence interval, EQD2 Gy: equivalent dose in 2-Gray fractions, MV: multivariable, UV: univariable.
| Toxicity rate for ≥G3 toxicity | Model dose prediction (EQD2 Gy) | 95% CI lower limit (EQD2 Gy) | 95% CI upper limit (EQD2 Gy) | Block bootstrapped 95% CI lower limit (EQD2 Gy) | Block bootstrapped 95% CI upper limit (EQD2 Gy) |
|---|---|---|---|---|---|
| MV model–without concurrent chemotherapy | |||||
| 5% | 94.2 | 82.1 | 106.4 | 79.6 | 142.8 |
| 10% | 111.6 | 98.9 | 124.3 | 96.1 | 174.4 |
| 20% | 130.4 | 112.5 | 148.3 | 104.5 | 212.0 |
| 30% | 142.9 | 120.3 | 165.5 | 109.6 | 236.7 |
| MV model–with concurrent chemotherapy | |||||
| 5% | 43.0 | 14.7 | 71.4 | −18.5 | 108.8 |
| 10% | 60.4 | 39.0 | 81.7 | 15.0 | 120.6 |
| 20% | 79.2 | 64.3 | 94.1 | 51.6 | 136.0 |
| 30% | 91.7 | 79.6 | 103.8 | 73.7 | 149.0 |