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Infection of an RHE model by 2 × 106 C. albicans cells. RHE infected by strains CAF2-1 and C4-SHB1.1 are shown at 6 and 22 h of incubation; RHE infected by strains SM1813c and SM1814c are shown at 12 h of incubation. Note the deep penetration and formation of vacuoles by SIT1+ strains (arrows).
