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Urinary steroid metabolites excretion rates (μg/24h) in 8 normal male subjects on dexamethasone and dexamethasone plus cortisol treatment. The results were compared by 2-sample Student s t test [mean (±SEM)].
| STEROID | Dexamethasone | Dexamethasone + Cortisol | P |
|---|---|---|---|
| Cortisol | 1.3 ± 0.7 | 52.6 ± 8.2 | 0.0004 |
| Cortisone | 3.4 ± 0.7 | 87.3 ±20.2 | 0.004 |
| 18-OH-F | 5.3 ± 2.7 | 10.9 ± 3.1 | 0.2 |
| 18-Oxo-F | 1.8 ± 0.4 | 11.6 ± 1.4 | 0.0001 |
