TABLE 4.

Concentrations of secreted soluble inflammatory markers in femoral artery endothelial cells harvested from 10 baboons after the basal diet or the high-cholesterol high-fat (HCHF) diet¹

Soluble marker	Basal diet	HCHF diet
IL-6 (pg/μg protein)	8.1 ± 1.5	5.8 ± 1.1
IL-8 (pg/μg protein)	0.11 ± 0.05	0.09 ± 0.004
GM-CSF (pg/μg protein)	<0.01	<0.01
INF-γ (pg/μg protein)	<0.01	<0.01
MCP-1 (pg/μg protein)	0.21 ± 0.11	0.44 ± 0.132
RANTES (pg/μg protein)	<0.01	<0.01
IL-1β (pg/μg protein)	0.01 ± 0.01	0.01 ± 0.01
sVCAM-1 (ng/mL)	86.0 ± 5.2	94.2 ± 7.0
sICAM-1 (ng/mL)	64.2 ± 2.4	64.3 ± 1.9

¹All values are $\overline{x}\pm \text{SEM}$. IL, interleukin; GM-CSF, granulocyte-macrophage colony-stimulating factor; INF-γ, interferon γ; MCP-1, monocyte chemoattractant protein 1; RANTES, regulated on activation normal T cell expressed and secreted factor; IL-1β, interleukin 1β; sVCAM-1, soluble vascular cell adhesion molecule 1; sICAM-1, soluble intercellular cell adhesion molecule 1.

²Significantly different from the basal diet, P < 0.01 (paired Student’s t test).