TABLE 5.

Changes in membrane-bound vascular cell adhesion molecule 1 (mVCAM-1) membrane-bound E-selectin (mE-selectin), and endothelial nitric oxide synthase (eNOS) concentrations in baboon femoral artery endothelial cell (BFAEC) extracts after exposure to various stimuli in vitro¹

	mVCAM-1		mE-selectin		eNOS
	Basal diet	HCHF diet	Basal diet	HCHF diet	Basal diet	HCHF diet
No treatment	0.77 ± 0.22	1.85 ± 0.532	0.08 ± 0.12	0.21 ± 0.182	196.5 ± 29.7	36.4 ± 21.92
TNF-α, 10 ng/mL	41.69 ± 13.223	16.13 ± 3.574	19.57 ± 22.62	7.68 ± 4.80	29.7 ± 21.83	4.3 ± 2.9
LPS, 1 μg/mL	17.18 ± 7.423	4.71 ± 1.113	5.01 ± 9.58	0.85 ± 0.81	10.0 ± 5.53	6.3 ± 2.8
Native LDL cholesterol, 100 μg/mL	3.22 ± 0.453	2.01 ± 0.82	0.09 ± 0.07	0.09 ± 0.01	28.5 ± 18.03	2.3 ± 1.3
oxLDL cholesterol, 100 μg/mL	2.17 ± 0.513	1.65 ± 0.43	0.01 ± 0.01	0.04 ± 0.02	3.5 ± 2.54	3.7 ± 1.7

¹All values are $\overline{x}\pm \text{SEM}$; n = 10 baboons. HCHF, high-cholesterol, high-fat; TNF-α, tumor necrosis factor α; LPS, lipopolysaccharide; oxLDL, oxidized LDL.

²Significantly different from the basal diet, P < 0.05.

^3,4Significantly different from no treatment of endothelial cells collected either after the basal diet or after the HCHF diet (paired Student’s t test with Bonferroni correction for multiple comparisons):

³P < 0.05,

⁴P < 0.01.