Table 2.
Gene cluster on Xq28
| Gene Symbol (Probe) | Name | †Fold change (qRT-PCR) | Rank | Function/Other information |
| ARHGAP4 | Rho-GAP GTPase | 1.4 (2.2) | 44 | Possible inhibitory role on stress fiber organization and microtubules |
| §CTAG1 | Cancer/testis antigen 1 | 2.2 (1.6) | 3 | |
| §CTAG2 | Cancer/testis antigen 2 | 1.3 (1.6) | 93 | |
| § *LOC389903 | Cancer antigen | 1.3 (NC) | 75 | |
| § **MAGEA2 | Cancer antigen | 1.3 (NC) | 73 | |
| RPL10 | Ribosomal protein | 1.6 (1.4) | 22 | Tumor suppressor |
| SSR4 | Signal sequence receptor/translocon associated protein delta | 1.4 (1.2) | 52 | Type I receptor in endoplasmic reticulum/intracellular protein transport |
| § *TRAG3 | Tumor antigen | 1.3 (NC) | 77 |
† "Fold change," top number is the relative expression of RARβ2 transduced cells/empty vector control cells from Agilent arrays. The number in parentheses is the relative expression of the same cells from qRT-PCR analysis, normalized by respective qRT-PCR RPLP0 expression.
NC = differential expression was not confirmed by qRT-PCR
§ Genes in the cancer/testis antigen superfamily
* Shares significant overlapping sequence within their respective 60 mer probes, differing by 2–3 nucleotides
** MAGEA2 60 mer probe shares significant sequence identity with MAGEA-3, -6, and -12 (differs by 1–2 nucleotides)