Table 1.
Immunohistochemical staining results of the prostate biopsy and lymph-node biopsy
| Marker | Prostate biopsy (Gleason 4, higher differentiation) | Prostate biopsy (Gleason 5, poorly differentiated) | Lymph-node biopsy (adenocarcinoma-like component) | Lymph-node biopsy (poorly differentiated NEPC) |
|---|---|---|---|---|
| AE1/AE3 | Not tested | Not tested | Positive | Positive |
| CK7 | Not tested | Not tested | Negative | Negative |
| CK20 | Not tested | Not tested | Negative | Negative |
| AMACR | Positive | Weak/negative | Partial positive | Negative |
| PSA | Weakly positive | Negative | Faint positive | Negative |
| AR | Positive | Partial positive | Partial positive | Negative |
| NSE | Negative | Positive | Not tested | Positive |
| Chromogranin A | Weak, non-specific positivity | Focal positive | Negative | Negative |
| Synaptophysin | Negative | Positive | Partial positive | Partial positive |
| CD56 | Negative | Positive | Positive | Positive |
| INSM1 | Negative | Positive | Positive | Positive |