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. 2025 Sep 16;18(4):1005–1019. doi: 10.1007/s40653-025-00728-8

Table 3.

Regression coefficients, standard errors (SE), and model summary information for simple mediation models assessing a) the effect that the baseline TADS total score (X) exerts on the change in the BDI sum score (Y) through the BRS sum score (M) and b) the effect that the baseline TADS factor score (X) exerts on the change in the BDI sum score (Y) through the BRS factor score (M). The results are adjusted for two possible confounders: age at baseline (U1) and gender (U2)

a. Sum scores model
Antecedent Consequent
Mediator (BRS) Dependent (BDI change)
Coeff SE p Coeff SE p
X (TADS) a −0.01 0.00  <.001 c’ −0.04 0.03 .22
M (BRS) b 2.17 0.82 .01
U1 Age a2 −0.06 0.03 .03 2 −0.83 0.38 .03
U2 Gender a3 −0.50 0.10  <.001 c’3 1.19 1.51 .43
Constant iM 4.60 0.46  <.001 iy 3.03 6.30 .63
R2 =.18 R2 =.06
F(21.21) = 293, p <.001 F(4.94) = 292, p <.001
ab = −0.03; Boot SE = 0.01; 95% CI (boot) = −0.04 to −0.01
b. Factor scores model
Antecedent Consequent
Mediator (BRS) Dependent (BDI change)
Coeff SE p Coeff SE p
X (TADS) a −0.24 0.06  <.001 c’ −0.80 0.67 .23
M (BRS) b 1.80 0.64 .01
U1 Age a2 −0.07 0.03 .03 2 −0.83 0.38 .03
U2 Gender a3 −0.62 0.13  <.001 c’3 1.35 1.51 .37
Constant iM 1.68 0.59 .01 iy 9.15 6.59 .17
R2 =.14 R2 =.06
F(16.17) = 295, p <.001 F(5.02) = 294, p <.001
ab = −0.43; Boot SE = 0.16; 95% CI (boot) = −0.77 to −0.14