Table 3.
Multivariable logistic regression model for prediction of positive ADAM questionnaire score
| OR (95%CI) | p-value | |
|---|---|---|
| Age | 1.027 (0.970, 1.088) | 0.36 |
| BMI (kg/m2) | ||
| ≤ 24.9 | Reference | |
| 25–29.9 | 1.997 (0.883, 4.518) | 0.097 |
| 30 + | 1.724 (0.632, 4.700) | 0.29 |
| Smoking | 0.85 | |
| No | Reference | |
| Yes | 0.906 (0.328, 2.502) | |
| Alcohol | 0.73 | |
| No | Reference | |
| Yes | 1.136 (0.555, 2.327) | |
| Log semen volume | 0.985 (0.417, 2.325) | 0.97 |
| Sperm motility | 1.005 (0.961, 1.051) | 0.83 |
| Log sperm morphology | 1.318 (0.856, 2.030) | 0.21 |
| Log sperm concentration | 0.974 (0.664, 1.426) | 0.89 |
| Sperm viability | 0.989 (0.959, 1.020) | 0.50 |
| DFI category | 0.58 | |
| < 30% | Reference | |
| ≥ 30% | 0.786 (0.337, 1.832) | |
| SHIM | ||
| Normal | Reference | |
| Mild | 3.926 (1.768, 8.718) | < 0.001 |
| Moderate/severe | 11.632 (3.804, 35.564) | < 0.001 |
| Testosterone | 0.961 (0.901, 1.025) | 0.23 |
| Log FSH | 1.241 (0.491, 3.135) | 0.65 |
| Log LH | 2.350 (0.686, 8.044) | 0.17 |
| Log prolactin | 1.935 (0.883, 4.242) | 0.099 |
DFI, DNA fragmentation index; BMI, body mass index; FSH, follicle-stimulating hormone; LH, luteinizing hormone; ADAM, The Androgen Deficiency in Aging Males; SHIM, The Sexual Health Inventory for Men
Bold values represent statistical significancy - a p-value <0.05