Table 2.
Binomial regression with logit link function to model the immaturity rate formulated as number of events (immature oocytes) per cohort (total collected oocytes) versus all variables that were significant from the univariate analyses. Non-linear associations were modelled with restricted cubic splines and model fits were compared using Akaike information criterion
| Predictors | Risk ratio | 95%CI | p-value |
|---|---|---|---|
| (Intercept) | 0.23 | 0.20–0.27 | < 0.001 |
| Duration of ovarian stimulation [< 11 days] | 0.45 | 0.38–0.54 | < 0.001 |
| Duration of ovarian stimulation [> 11 days] | 0.89 | 0.71–1.11 | 0.306 |
| Trigger type [GnRH agonist versus urinary hCG] | 0.92 | 0.88–0.95 | < 0.001 |
| Ovulation trigger to oocytes’ denudation interval [< 39 h] | 0.69 | 0.60–0.80 | < 0.001 |
| Ovulation trigger to oocytes’ denudation interval [> 39 h] | 0.99 | 0.86–1.13 | 0.870 |
| Ratio COC to fol1icle > 14 mm at ovulation trigger [< 1.13] | 3.11 | 2.63–3.67 | < 0.001 |
| Ratio COC to fol1icle > 14 mm at ovulation trigger [> 1.13] | 1.52 | 1.34–1.71 | < 0.001 |