Table 3.

Most advanced neoplastic lesion on follow-up surveillance colonoscopy in individuals at moderate familial risk (groups 1-3). Values are numbers (percentages) of patients

		Most advanced lesion on follow-up colonoscopy
Most advanced lesion on initial colonoscopy	Normal	Metaplastic polyp	Simple adenoma	Multiple simple adenomas	High risk adenoma	Colorectal cancer
Normal (n=545)	406 (73)	53 (10)	78 (15)	3 (1)	5 (1)	0 (0)
Metaplastic polyp (n=67)	34 (52)	17 (25)	13 (19)	1 (1)	2 (3)	0 (0)
Simple adenoma (n=112)	51 (49)	16 (14)	35 (30)	6 (5)	3 (2)	1 (1)
Multiple simple adenomas (n=12)	3 (29)	2 (18)	5 (41)	2 (13)	0 (0)	0 (0)
High risk adenoma (n=23)	4 (26)	4 (21)	8 (34)	3 (7)	4 (12)	0 (0)

Percentages are of the number with each initial finding and are adjusted for age and sex.