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. 2026 Jan 12;12:1722081. doi: 10.3389/fnut.2025.1722081

Table 2.

Comparison of the cumulative days of each symptom during the intake period.

Symptoms Group 1–4 W 1–8 W 1–12 W
Without With p-value Without With p-value Without With p-value
Runny nose Placebo 2,187 417 0.026* 4,277 931 0.419 6,482 1,330 0.248
LG2055 2,172 488 4,336 984 6,565 1,415
Nasal congestion Placebo 2,277 327 0.006* 4,517 691 0.004* 6,756 1,056 <0.001*
LG2055 2,390 270 4,714 606 7,066 914
Sneezing Placebo 2,392 212 0.256 4,579 629 <0.001* 6,789 1,023 <0.001*
LG2055 2,466 194 4,797 523 7,128 852
Sore throat Placebo 2,323 281 0.258 4,667 541 0.848 7,056 756 0.471
LG2055 2,346 314 4,774 546 7,180 800
Hoarseness Placebo 2,431 173 <0.001* 4,857 351 <0.001* 7,303 509 <0.001*
LG2055 2,576 84 5,120 200 7,669 311
Cough Placebo 2,383 221 <0.001* 4,788 420 <0.001* 7,174 638 <0.001*
LG2055 2,511 149 5,038 282 7,566 414
Headache Placebo 2,423 181 <0.001* 4,847 361 <0.001* 7,283 529 <0.001*
LG2055 2,534 126 5,100 220 7,674 306
General malaise Placebo 2,421 183 0.036* 4,826 382 0.004* 7,266 546 <0.001*
LG2055 2,511 149 5,004 316 7,544 436
Chills Placebo 2,504 100 0.066 4,997 211 <0.001* 7,546 266 <0.001*
LG2055 2,583 77 5,178 142 7,795 185
Feverishness Placebo 2,544 60 <0.001* 5,075 133 <0.001* 7,628 184 <0.001*
LG2055 2,631 29 5,251 69 7,875 105
Fatigue Placebo 2,328 276 0.253 4,695 513 0.447 7,065 747 0.428
LG2055 2,404 256 4,820 500 7,247 733
Feeling unwell Placebo 2,511 93 0.019* 5,016 192 <0.001* 7,555 257 0.036*
LG2055 2,595 65 5,186 134 7,763 217

*Significant difference between the two groups (p < 0.05).