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. 2026 Jan 12;12:1722081. doi: 10.3389/fnut.2025.1722081

Table 6.

Comparison of the cumulative days of each symptom during the intake period (young participants).

Symptoms Group 1–4 W 1–8 W 1–12 W
Without With p-value Without With p-value Without With p-value
Runny nose Placebo 702 194 0.043* 1,379 413 0.007* 2,115 573 0.053
LG2055 646 138 1,267 301 1,903 449
Nasal congestion Placebo 738 158 0.128 1,476 316 0.180 2,229 459 0.910
LG2055 668 116 1,319 249 1,954 398
Sneezing Placebo 815 81 0.323 1,540 252 1.000 2,270 418 0.667
LG2055 701 83 1,348 220 1,997 355
Sore throat Placebo 734 162 <0.001* 1,498 294 <0.001* 2,281 407 <0.001*
LG2055 692 92 1,376 192 2,085 267
Hoarseness Placebo 796 100 <0.001* 1,596 196 <0.001* 2,398 290 <0.001*
LG2055 734 50 1,454 114 2,199 153
Cough Placebo 813 83 0.131 1,633 159 0.148 2,452 236 0.006*
LG2055 728 56 1,451 117 2,195 157
Headache Placebo 804 92 <0.001* 1,616 176 <0.001* 2,440 248 <0.001*
LG2055 750 34 1,494 74 2,253 99
General malaise Placebo 775 121 0.001* 1,555 237 0.005* 2,361 327 <0.001*
LG2055 717 67 1,410 158 2,135 217
Chills Placebo 833 63 0.001* 1,670 122 <0.001* 2,537 151 <0.001*
LG2055 757 27 1,512 56 2,285 67
Feverishness Placebo 854 42 0.008* 1,695 97 <0.001* 2,559 129 <0.001*
LG2055 766 18 1,532 36 2,308 44
Fatigue Placebo 740 156 0.144 1,521 271 0.599 2,320 368 0.137
LG2055 669 115 1,320 248 1,995 357
Feeling unwell Placebo 845 51 <0.001* 1,691 101 <0.001* 2,550 138 <0.001*
LG2055 769 15 1,531 37 2,297 55

*Significant difference between the two groups (p < 0.05).