FIG. 4.

Time course of lethality in control and P. acnes-sensitized IFN-γR^−/− mice infected with serovar Typhimurium. Mice received killed P. acnes (25 μg/g) administered i.v. or remained untreated (controls). One week later groups of 5 to 10 animals were infected with 10⁴ or 10⁷CFU of serovar Typhimurium i.v., and lethality was recorded daily.