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. 2005 Oct 26;102(45):16221–16226. doi: 10.1073/pnas.0505089102

Table 4. Correlation of residue burial with activity for mutants of T4 lysozyme.

Active mutants,* %
ACC, % Total no. of sites Ala Glu Lys Arg
0–5 32 89 23 8 14
5–15 28 96 72 68 84
15–40 32 96 86 61 68
>40 59 100 98 92 100
*

Data taken from ref. 31