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. 2025 Dec 8;67(2):96–103. doi: 10.3349/ymj.2025.0128

Table 3. Risk of Retinal Vascular Occlusive Disease in Patients with Acute Coronary Syndrome Compared with Controls, Stratified by Age Group and Sex, in the Established Cohort from the National Health Insurance Service Database of South Korea.

Strata Control cohort UA cohort MI cohort HR_UA (95% CI)* HR_MI (95% CI)*
N of events IR* (95% CI) N of events IR* (95% CI) N of events IR** (95% CI)
RVOD according to age group (yr)
Age <65 959 254.38 (254.33–354.43) 936 390.64 (390.56–390.72) 92 261.74 (261.57–261.91) 1.45 (1.31–1.60) 1.07 (0.86–1.34)
Age ≥65 1100 315.32 (315.26–315.38) 1324 648.34 (648.23–648.45) 105 543.87 (543.54–544.20) 1.79 (1.63–1.96) 1.53 (1.24–1.89)
RVOD according to sex
Male 1350 265.88 (265.84–265.92) 1481 476.10 (476.02–476.18) 159 354.83 (354.66–355.00) 1.65 (1.51–1.79) 1.40 (1.18–1.66)
Female 709 325.09 (325.01–325.17) 779 586.81 (586.68–586.94) 38 393.98 (393.58–394.38) 1.65 (1.47–1.85) 1.16 (0.83–1.64)

UA, unstable angina; MI, myocardial infarction; IR, incidence rate; CI, confidence interval; HR, hazard ratio; RVOD, retinal vascular occlusive disease.

*Adjusted for age, sex, body mass index, income, mortality, smoking, alcohol consumption, total cholesterol, systolic blood pressure, fasting glucose, and history of atrial fibrillation.