FIG. 1.
Effect of indomethacin and/or IL-12 treatment on infection. BALB/c mice were given either indomethacin (20 μg/ml in 0.4% ethanol) or 0.4% ethanol in drinking water starting 1 day before infection with 2 × 105 L. major metacyclic promastigotes. Treated and control mice received a total of six intralesional injections of 0.2 μg of either IL-12 or PBS given every 3rd day starting on day 15 of infection. Lesion size was measured weekly for 8 weeks and expressed as the difference in thickness between the infected and the uninfected contralateral footpads. Values are the mean ± standard deviation of four to five mice per group and are representative of results of two separate experiments.