Table 2.

Summary of potential video directly observed treatment (video DOT) use cases and goals.

Stage of care	Potential video DOT use case	Outcomes of interest
Treatment initiation	Monitor initial methadone dose titration	Shortened time to reach therapeutic dose Improved adherence or reduction in missed doses
Treatment monitoring	Provide additional support for patients increasing take-home doses Enable virtual callbacks for patients on take-home doses Provide encouragement or positive reinforcement to patients for consistent engagement or adherence (eg, through asynchronous video or SMS text messages from the care team) Provide additional structure for patients needing short-term exceptions (eg, an unexpected need for take-home doses) Provide monitoring for patients with split dosing	Increased take-home doses per patient Improved MOUDa adherence and days of coverage (ie, fewer missed doses) Improved engagement and retention in care Reduced diversion or misuse of methadone Reduced illicit opioid and polysubstance use Reduced time and cost associated with transportation and access burden for patients Improve recognition and responsiveness to patient health needs (eg, communication about side effects and dosing issues) Increased patient and health care provider satisfaction with care delivery
Treatment completion and transition to the next phase of care	Monitor transition to buprenorphine or other MOUD	Shortened time to reach therapeutic dose

^aMOUD: medications for opioid use disorder.