FIG. 5.

Differential expression of ADAR1 splice variants in mouse tissues. PCR products were generated using cDNA templates prepared with RNA isolated from cultured MEF cells that were untreated (C) or treated with IFN-αA/D (IFN) and from the brain and liver of uninfected (U) BALB/c mice or from mice 6 days after infection with WT Salmonella. a and b designate the PCR fragments corresponding to the ADAR1-a and b splice variants. Expression of GAPDH in mouse tissues and MEF cells was analyzed by PCR using the same cDNA templates as were used for ADAR1 expression. Std (kb): numbers correspond to standard DNA fragments in kilobases.