Table 5.
Characteristics associated with concordance between self-reports and medical records, Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS), 2018 (n=184).†
| Medications used episodically | Medications used chronically | |||||||
|---|---|---|---|---|---|---|---|---|
| Concordant n=139 | Discordant n=45 | Univariate analysis | Multivariable analysis | Concordant n=171 | Discordant n=13 | Univariate analysis | Multivariable analysis | |
| n | n | OR (95%CI) | OR (95%CI) | n | n | OR (95%CI) | OR (95%CI) | |
| Case/control status | ||||||||
| Case | 73 | 27 | ref | ref | 92 | 8 | ref | ref |
| Control | 66 | 18 | 1.35 (0.70, 2.70) | 1.47 (0.66, 3.33) | 79 | 5 | 1.33 (0.44, 4.35) | 2.56 (0.66, 11.11) |
| Interview time | ||||||||
| 6 months or less | 52 | 22 | ref | ref | 69 | 5 | ref | ref |
| More than 6 months | 87 | 23 | 1.60 (0.81, 3.13) | 1.32 (0.62, 2.80) | 102 | 8 | 0.95 (0.29, 2.97) | 0.69 (0.18, 2.47) |
| Interview language | ||||||||
| English | 95 | 26 | ref | ref | 111 | 10 | ref | ref |
| Spanish | 34 | 17 | 0.55 (0.27, 1.13) | 0.59 (0.20, 1.68) | 48 | 3 | 1.31 (0.40, 5.35) | 0.29 (0.02, 3.19) |
| Nativity | ||||||||
| US-born | 84 | 21 | ref | ref | 92 | 10 | ref | ref |
| Foreign-born | 48 | 22 | 0.57 (0.28, 1.13) | 0.55 (0.20, 1.60) | 67 | 3 | 2.19 (0.68, 8.94) | 2.70 (0.30, 48.90) |
| Educational attainment | ||||||||
| High school or less | 56 | 18 | 1.06 (0.53, 2.14) | 1.10 (0.49, 2.73) | 70 | 4 | 1.66 (0.54, 5.89) | 1.74 (0.41, 9.16) |
| More than high school | 73 | 25 | ref | ref | 89 | 9 | ref | ref |
| Maternal Occupational Status | ||||||||
| No | 33 | 10 | ref | ref | 41 | 2 | ref | |
| Yes | 96 | 33 | 0.90 (0.39, 1.96) | 0.81 (0.33, 1.89) | 118 | 11 | 0.62 (0.12, 2.22) | -- |
| Health insurance in early pregnancy | ||||||||
| No | 19 | 4 | ref | ref | 21 | 2 | ref | |
| Yes | 110 | 39 | 0.65 (0.19, 1.78) | 0.31 (0.08, 1.04) | 138 | 11 | 1.40 (0.26, 5.20) | -- |
| Parity | ||||||||
| None | 42 | 18 | ref | ref | 57 | 3 | ref | ref |
| One or more | 93 | 27 | 1.48 (0.73, 2.95) | 1.54 (0.68, 3.48) | 112 | 8 | 0.81 (0.19, 2.73) | 1.02 (0.23, 3.88) |
| mean (SD) | mean (SD) | mean (SD) | mean (SD) | |||||
| Maternal age at delivery | 29.9 (6.0) | 30.1 (6.1) | 1.00 (0.94, 1.05) | 0.97 (0.91, 1.04) | 29.8 (6.0) | 32.5 (5.6) | 0.93 (0.84, 1.02) | 0.89 (0.77, 1.01) |
SD= standard deviation
†
The multivariable models included variables for case/control status, time between delivery and interview, interview language, age, educational attainment, occupation status, health insurance during early pregnancy, and parity. Singleton birth and birth outcome were not included in this analysis due to small numbers. Additionally, health insurance in early pregnancy and maternal occupational status were not included in the multivariable model for medications used chronically.