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Kaplan–Meier estimates for immune checkpoint inhibitor (ICI)-based therapy according to the early tumor shrinkage (ETS) status. (A) Progression-free survival (PFS) and (B) overall survival (OS) in ICI + chemotherapy (chemo). (C) PFS and (D) OS in nivolumab + ipilimumab (nivo + ipi). CI, confidence interval; NR; not reached.
