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. 2025 Apr 3;8:100159. doi: 10.1016/j.esmogo.2025.100159

Figure 2.

Figure 2

Weights for the primary analysis of the SLoS model determined by the ‘swing-weighting’ method. AE, adverse event; ECG QT, electrocardiogram QT prolongation; GI, gastrointestinal; ORR, objective response rate; OS, overall survival; PFS, progression-free survival; SLoS, Scale Loss Score. ECG QT prolongation is based on grade ≥2 events of standard MedDRA query (broad-scope search) of torsade de pointes/QT prolongation. Fatigue events, grade ≥2 asthenia or fatigue. GI events, any grade of diarrhea, retching and vomiting, or grade ≥2 nausea.