Table 2.

Health care utilization outcomes

Outcome variable	NF 1 cases (n = 1,210) 23,672 person years	Controls (n = 6,050) 1,13,181 person years	p-value	Rate Ratio (95% CI)
ED visits
Yes, n (%)	1,096 (90.6%)	4,956 (81.9%)	< 0.0001
Mean number of visits (SD)	8.8 (11.8)	6.8 (8.5)	< 0.0001
Rate of use	0.41	0.30		1.11 (1.04–1.19)
Hospitalizations
Yes, n (%)	999 (82.6%)	2,065 (34.1%)	< 0.0001
Mean number of visits (SD)	3.02 (3.39)	2.34 (2.98)	< 0.0001
Rate of use	0.13	0.04		2.66 (2.43–2.91)
Primary care visits
Yes, n (%)	1,179 (97.4%)	5,828 (96.3%)	0.0552
Mean number of visits (SD)	70.35 (78.14)	51.76 (54.00)	< 0.0001
Rate of use	3.49	2.67		1.15 (1.10–1.21)
Specialist visits
Yes, n (%)	1,205–1,209 (99%)	5,378 (88.9%)	< 0.0001
Mean number of visits (SD)	70.96 (65.90)	26.97 (39.50)	< 0.0001
Rate of use	3.61	1.28		2.34 (2.18–2.51)
Same-day surgery visit
Yes, n (%)	663 (54.8%)	2,168 (35.8%)	< 0.0001
Mean number of visits (SD)	3.42 (3.88)	2.39 (3.42)	< 0.0001
Rate of use	0.10	0.05		1.62 (1.47–1.79)

ED: Emergency Department

Rate Ratio through binominal modelling adjusted by age, sex, income quintile, rurality and ADG. Specialty visits presented as range, to minimize risk of identification, given low number of individuals with NF1 without specialty visits

Mean number of visits on those individuals with ≥ 1 visit during the study window