Table 2.
Change in WOMAC pain scores at 6, 12, 18 and 24 months† and knee related physical function and stiffness at 24 months
Outcome
|
No of participants
|
Baseline
|
Mean difference at 24 months†
|
95% confidence interval for mean difference
|
df
|
F
|
P
|
Effect size
|
---|---|---|---|---|---|---|---|---|
Primary | ||||||||
Knee pain at 24 months*: | ||||||||
Exercise | 467 | 7.15 | −0.82 | −1.3 to −0.3 | 1 and 779 | 11.14 | 0.001 | 0.25 |
Non-exercise | 316 | 7.35 | ||||||
Telephone | 393 | 7.10 | −0.16 | −0.6 to 0.3 | 1 and 779 | 0.45 | 0.50 | 0.05 |
Non-telephone | 390 | 7.40 | ||||||
Knee pain at 6 months: | ||||||||
Exercise | 467 | 7.15 | −0.61 | −1.0 to −0.2 | 1 and 779 | 8.64 | 0.003 | 0.21 |
Non-exercise | 316 | 7.35 | ||||||
Knee pain at 12 months: | ||||||||
Exercise | 467 | 7.15 | −0.61 | −1.0 to −0.2 | 1 and 779 | 7.80 | 0.005 | 0.20 |
Non-exercise | 316 | 7.35 | ||||||
Knee pain at 18 months: | ||||||||
Exercise | 467 | 7.15 | −0.69 | −1.1 to −0.2 | 1 and 779 | 9.10 | 0.003 | 0.22 |
Non-exercise | 316 | 7.35 | ||||||
Secondary | ||||||||
Physical function: | ||||||||
Exercise | 466 | 23.15 | −2.57 | −4.1 to −1.1 | 1 and 778 | 11.44 | 0.001 | 0.25 |
Non-exercise | 316 | 22.97 | ||||||
Stiffness: | ||||||||
Exercise | 470 | 3.42 | −0.29 | −0.5 to −0.1 | 1 and 782 | 6.44 | 0.01 | 0.18 |
Non-exercise | 316 | 3.46 |
Interaction of exercise and telephone (P=0.54).
Negative values for mean differences reflect improvements in knee symptoms compared with baseline.