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. 2025 Dec 19;16(1):4. doi: 10.3390/biom16010004
Abbreviation Definition
OXCT1 3-Ketoacid CoA-transferase 1
WHO World Health Organization
IARC International Agency for Research on Cancer
AcAc acetoacetate
β-HB 3-hydroxybutyrate
Acetyl-CoA acetyl-coenzyme A
TCA cycle tricarboxylic acid cycle
HCC hepatocellular carcinoma
CRC colorectal cancer
BCa bladder cancer
OS osteosarcoma
PCa prostate cancer
CS chondrosarcoma
GC glioma, gastric cancer
NPC nasopharyngeal carcinoma
SCOT succinyl-CoA:3-ketoacid CoA Transferase
CoA coenzyme A
OXCT2 or h-Scot-t succinyl CoA:3-oxoaci ketoacid CoA-transferase 2
GLUT1 Glucose Transporter Type 1
H3K27me3 trimethylation of lysine 27 on histone H3
PTM Post-Translational Modification
SIRT3 Sirtuin 3
Kbhb lysine β-hydroxybutyrylation
AMPKα2 AMP-activated protein kinase alpha 2 subunit
AMPK AMP-activated protein kinase
IGF1 Insulin-like growth factor 1
ERK2 extracellular signal-regulated kinase 2
SUCLA2 succinate-CoA ligase ADP-forming subunit beta
AHA Acetohydroxamic acid
KD ketogenic diet
TAM tumor-associated macrophages
Arg1 arginase 1
LACTB serine β-lactamase-like protein
PISD phosphatidylserine decarboxylase
LPE lysophosphatidylethanolamines
PE phosphatidylethanolamines
SREBP1 sterol regulatory element-binding protein 1
bHLH-Zip basic helix-loop-helix leucine zipper
NSCLC non-small cell lung cancer
EMT epithelial–mesenchymal transition
PDAC pancreatic ductal adenocarcinoma
DNMT DNA methyltransferase
circRNAs circular RNAs
lncRNAs long non-coding RNAs
circ-OXCT1 CircRNA 3-oxoacid CoA-transferase 1
ceRNA competitive endogenous RNA
miRNA microRNA
SLC1A5 solute carrier family 1 member 5
lncRNA OXCT1-AS1 antisense RNA1 of lncRNA OXCT1
LEF1 Lymphoid enhancer factor 1
GBM glioblastoma
GEPIA Gene Expression Profiling Interactive Analysis
TCGA Cancer Genome Atlas
mOS median Overall Survival
CRPC castration-resistant prostate cancer
RFS Recurrence-Free Survival
IFO ifosfamide
HDACs histone deacetylases
EAE experimental autoimmune encephalomyelitis