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. 2005 Nov 17;115(12):3409–3417. doi: 10.1172/JCI25040

Figure 8.

Figure 8

Effects of Hb infusions with and without inhaled NO. Infusion of cell-free Hb led to increases in SVRI and pulmonary vascular resistance index that were attenuated by inhaled NO (A and B). In animals breathing air (n = 2), the cell-free Hb remained predominantly oxyhemoglobin (C). In contrast, in animals breathing NO (n = 2), the cell-free Hb was converted to methemoglobin (D).