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. 2005 Nov 17;115(12):3494–3505. doi: 10.1172/JCI26052

Figure 6.

Figure 6

Glucose homeostasis in Insr+/–Timp3+/–, Insr+/–Tace+/–, Insr+/–, Timp3+/–, Tace+/–, and WT littermates at 3 months. Fasted glucose (A), fasted insulin (B), fed glucose (C), and fed insulin (D) levels in mice (n = 8–10 per group). Data are expressed as mean ± SD. †P < 0.001 for Insr+/–Timp3+/– versus Timp3+/–, Tace+/–, and WT mice by 1-way ANOVA; #P < 0.01 for Insr+/–Timp3+/– versus Insr+/– and Insr+/–Tace+/– mice; *P < 0.05 for Insr+/–Timp3+/– versus all the other genotypes by 1-way ANOVA. (E) Glucose levels after intraperitoneal glucose load. Data are expressed as mean ± SD (n = 5 per group). *P < 0.05 for Insr+/–Timp3+/– versus other genotypes by 2-way ANOVA. (F) Insulin tolerance test (0.75 U kg–1). Data are expressed as mean ± SD (n = 5 per group). *P < 0.05 for Insr+/–/Timp3+/– versus other genotypes by 2-way ANOVA.