| SASP | senescence-associated secretory phenotype |
| TME | tumor microenvironment |
| MDSCs | myeloid-derived suppressor cells |
| IL-6 | interleukin-6 |
| TNF-α | tumor necrosis factor- α |
| PD-1 | programmed death-1 |
| COAD | colon adenocarcinoma |
| FDR | false discovery rate |
| OS | overall survival |
| HR | hazard ratio |
| CSRS | cellular senescence-related signature |
| KEGG | Kyoto Encyclopedia of Genes and Genomes |
| GO | Gene Ontology |
| TICA | The Cancer Immunome Atlas |
| IPS | immunophenotype |
| ROC | Receiver Operating Characteristic |
| AUC | area under curve |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| SERPINE1 | serpin family E member 1 |
| FOXD1 | forked box protein D1 |
| ING5 | inhibitor of growth protein 5 |
| OXTR | oxytocin receptor |
| PHGDH | phosphoglycerol dehydrogenase |
| SNAI1 | snail family transcriptional repressor 1 |
| LIMK1 | LIM domain kinase 1 |
| CASP2 | cysteinyl aspartate specific proteinase 2 |