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. 2026 Jan 16;15(2):166. doi: 10.3390/cells15020166
PCa Prostate cancer
MMP-2 matrix metalloproteinase-2
eHSP90α Extracellular heat shock protein 90α
KO knockout
KD knockdown
KLK6 kallikrein-related peptidase 6
HSP90 heat shock protein 90
MMP matrix metalloproteases
ECM Extracellular matrix
BrCa Breast cancer
ATCC American Type Culture Collection
rEGF recombinant epidermal growth factor
BPE bovine pituitary extract
HS heat shock
SFM serum-free media
CF cell fraction
CM conditioned media
DQ dequenching
h hour
PCR Polymerase chain reaction
DAPI 4′,6-diamidino-2-phenylindole
AR Androgen receptor
HSR heat shock response
iHSP90α Intracellular heat shock protein 90α
PPI protease/phosphatase inhibitors
EV Empty vector control
PI Protease inhibitors
PhI Phosphatase inhibitors
MME membrane metallo-endopeptidase
siNegt Non-targeting negative control siRNA Smartpool
siMME siRNA Smartpool targeting MME transcript
siKLK6 siRNA Smartpool targeting KLK6 transcript
HNSCC head and neck squamous cell carcinoma