Figure 3.

Intrahost mutational profile of CHIKV in samples derived from Ae. aegypti and humans. (A) Mutation density across the CHIKV genome, estimated using 500-bp sliding windows, comparing genomes from human and mosquito samples. (B) Number of shared mutations (present in two or more samples) and unique mutations (detected in only one sample) across viral proteins, stratified by host and mutation type (synonymous versus nonsynonymous). (C) Allele frequency distribution of shared and unique mutations in human and mosquito samples, categorized by mutation type (synonymous or nonsynonymous). Colours represent either the host species or the mutation classification.