Skip to main content
. 2026 Jan 20;17(1):108. doi: 10.3390/genes17010108
AAV Adeno-associated virus
AD-MSCs Adipose-derived mesenchymal stromal cells
ATMP Advanced therapy medicinal product
B-ALL B-cell acute lymphoblastic leukemia
bFGF Basic fibroblast growth factor
BM-MSC Bone marrow-derived mesenchymal stromal cell
CAF Cancer-associated fibroblast
CTC Circulating tumor cell
CXCL12 C-X-C motif chemokine ligand 12 (stromal cell-derived factor-1, SDF-1)
CXCR4 C-X-C chemokine receptor type 4
EGF Epidermal growth factor
EMT Epithelial-to-mesenchymal transition
ERK Extracellular signal-regulated kinase
EV Extracellular vesicle
GDEPT Gene-directed enzyme prodrug therapy
HCC Hepatocellular carcinoma
HE Hospital exemption
HGF Hepatocyte growth factor
HIF-1α Hypoxia-inducible factor-1 alpha
HLA-DR Human leukocyte antigen—DR isotype
HSV-TK Herpes simplex virus thymidine kinase
IDO Indoleamine 2,3-dioxygenase
IFN-β Interferon-beta
IL-6 Interleukin-6
IL-8 Interleukin-8
IL-10 Interleukin-10
ITGA5 Integrin alpha-5
LLC Lewis lung carcinoma
MAPK Mitogen-activated protein kinase
MCP-1 Monocyte chemoattractant protein-1
MET Mesenchymal-to-epithelial transition
MNP Magnetic nanoparticle
MSC Mesenchymal stromal/stem cell
MSC-EV Mesenchymal stromal/stem cell-derived extracellular vesicle
NK Natural killer (cell)
NSCLC Non-small cell lung cancer
NTR Nitroreductase
OV / OVs Oncolytic virus / oncolytic viruses
PDAC Pancreatic ductal adenocarcinoma
PDGF Platelet-derived growth factor
PDGFR-β Platelet-derived growth factor receptor beta
PGE2 Prostaglandin E2
PLGA Poly(lactide-co-glycolide)
PNP Purine nucleoside phosphorylase
SDF-1 Stromal cell-derived factor-1 (CXCL12)
TME Tumor microenvironment
T-VEC Talimogene laherparepvec
TGF-β Transforming growth factor-beta
TK Thymidine kinase
TKA168H HSV-TK mutant variant TKA168H
TMZ Temozolomide
TNF-α Tumor necrosis factor-alpha
TRAIL Tumor necrosis factor-related apoptosis-inducing ligand
VEGF Vascular endothelial growth factor