Skip to main content
. 2026 Jan 9;15(2):541. doi: 10.3390/jcm15020541
ActRIIA Activin type II receptor A
ActRIIB Activin receptor type II
ActRIIB Activin type II receptor B
AMPK AMP-activated protein kinase
ATP Adenosine triphosphate production
CDC Centers for Disease Control and Prevention
FDA Food and Drug Administration
FFM Fat-free mass
FoxO1/3 Forkhead transcription factors 1 and 3
GDF11 Growth differentiation factor 11
GHRH Growth hormone-releasing hormone
GHS-R1a Growth hormone secretagogue receptor type 1a
GIP RA Glucose-dependent insulinotropic polypeptide receptor agonist
GIP-1 Glucagon-like peptide-1
GIP/GLP-1 RA or dual agonist Dual glucagon-like peptide-1 receptor/glucose-dependent insulinotropic polypeptide receptor agonist
GLP Glucose-dependent insulinotropic polypeptide
GLP-1 RAs Glucagon-like peptide-1 receptor agonists
GR Glucocorticoid receptor
HIV Human immunodeficiency virus
IGF Insulin-like growth factor
IL-6 Interleukin 6
JAK/STAT3 Janus Kinase (JAK)/Signal Transducer and Activator of Transcription (STAT) 3
LBM Lean body mass
LC3 Microtubule-associated protein 1 light chain 3
mTORc1 Mechanistic target of rapamycin complex 1
MuRF1 Muscle ring finger 1
MyHC Myosin heavy chain
MyoD Myoblast determination protein 1
MyoG Myogenin
NFκB Nuclear Factor kappa-light-chain-enhancer of activated B cells
NPY Neuropeptide Y
NRF-1 Nuclear respiratory factor 1
NRF-3 Nuclear respiratory factor 3
Pax7 Paired box gene 7
PGC-1α Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
PI3K Phosphatidylinositol-3 kinase
SARM Selective androgen receptor modulator
SM Skeletal muscle
SMAD2/3 Small mother against decapentaplegic 2/3
T2DM Type 2 diabetes mellitus
TFAM Mitochondrial transcription factor A
TNF-α Tumor necrosis factor alpha
TSC2 Tuberous sclerosis complex 2
U.S. United States
ULK1 Unc-51-like kinase 1