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. 2026 Jan 15;31(2):306. doi: 10.3390/molecules31020306
HDAC Histone Deacetylase
HDACs Histone Deacetylases
HATs Histone Acetyl Transferases
HDAC8 Histone Deacetylase 8
HDACi Histone Deacetylase Inhibitor
FDA Food and Drug Administration
PTM Post-Translational Modification
DFT Density Functional Theory
PCM Polarizable Continuum Model
HSAB Hard and Soft Acids and Bases
B3LYP Becke, 3-parameter, Lee-Yang-Parr hybrid functional
ZPE Zero-Point Energy
ΔE1 Change in Electronic Energy (gas phase)
ΔG1 Change in Gibbs Free Energy (gas phase)
ΔG32 Change in Gibbs Free Energy in Methanol (ε = 32)
ΔG78 Change in Gibbs Free Energy in Water (ε = 78)
ML4 Tetracoordinated Metal–Ligand Complex
ML5 Pentacoordinated Metal–Ligand Complex
ML6 Hexacoordinated Metal–Ligand Complex