SCs	Synthetic cannabinoids
NPS	New psychoactive substances
CB1	Cannabinoid receptor type 1
THC	Δ9-tetrahydrocannabinol
HLM	Human liver microsomes
CYP450	Cytochrome P450 enzyme family
UHPLC	Ultra-high-performance liquid chromatography
UHPLC–QE Orbitrap–MS	Ultra-high-performance liquid chromatography–Q Exactive Orbitrap mass spectrometry
LC–MS	Liquid chromatography–mass spectrometry
HRMS	High-resolution mass spectrometry
MS/MS	Tandem mass spectrometry
MS2	Secondary mass spectrometry
MS1	Precursor ion full-scan mass spectrometry
NCE	Normalized collision energy
AGC	Automatic gain control
IT	Injection time
m/z	Mass-to-charge ratio
ppm	Parts per million
ESI	Electrospray ionization
PBS	Phosphate-buffered saline
FA	Formic acid
ACN	Acetonitrile
NADPH	Nicotinamide adenine dinucleotide phosphate
AUs	Arbitrary units