APCs	antigen-presenting cells
ATP	adenosine triphosphate
CD	cluster of differentiation
CPS	combined positive score
CSF1	colony stimulating factor 1
CTLA-4	cytotoxic T-lymphocyte-associated protein 4
DAMPs	damage-associated molecular patterns
dMMR	defective mismatch repair system
DNA	deoxyribonucleic acid
EFS	event-free survival
EGF	epidermal growth factor
FDA	U.S. Food and Drug Administration
FGF2	fibroblast growth factor 2
GnRH	gonadotropin-releasing hormone
HER2	human epidermal growth factor receptor 2
HIF-1	hypoxia-induced factor 1
HLA	Human leukocyte antigen
HMGB1	high-mobility group box 1
HR	hormone receptor
IC	immune cells
IDO1	Indoleamine 2,3-dioxygenase 1
IHC	immunohistochemical
IFN	interferon
irAEs	immune-related adverse events
LAG3	lymphocyte-activation gene 3
MDSCs	myeloid-derived suppressor cells
MHC	major histocompatibility complex
MMR	mismatch repair
NK	natural killer cells
NKG2A	Natural Killer Group 2, Member A
OS	overall survival
PFS	progression-free survival
pCR	pathological complete response
PD-1	programmed cell death protein 1
PD-L1	programmed death-ligand 1
PR	progesterone receptor
PSGL-1	P-selectin glycoprotein ligand-1
TAMs	tumour-associated macrophages
Tc	cytotoxic lymphocyte
TC	tumour cells
TGF-β	transforming growth factor beta
TIGIT	T cell immunoreceptor with Ig and immunoreceptor tyrosine-based inhibitory motif domains
TILs	tumour-infiltrating lymphocytes
TMB	tumour mutational burden
TME	tumour microenvironment
TNBC	triple-negative breast cancer
TNFα	tumour necrosis factor alpha
Tregs	regulatory T cells
VEGF-A	vascular endothelial growth factor A
VSIG-3	V-set and immunoglobulin domain-containing protein 3