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. 2026 Jan 14;19(1):149. doi: 10.3390/ph19010149
ATCC American Type Culture Collection
CRC Colorectal cancer
DMEM Dulbecco’s Modified Eagle Medium
FBS Fetal bovine serum
SDS Sodium dodecyl sulfate
SDS-PAGE Sodium dodecyl sulfate–polyacrylamide gel electrophoresis
PBS Phosphate-buffered saline
BSA Bovine serum albumin
RIPA RadioImmunoPrecipitation Assay
HRP Horseradish peroxidase
HEEF Hydroethanolic extract of fresh corms
HEES Hydroethanolic extract of stored corms
HPLC High-performance liquid chromatography
ESI Electrospray ionization
QTOF Quadrupole time-of-flight
MS Mass spectrometry
MS/MS Tandem mass spectrometry
DDA Data-dependent acquisition
ADAP Automated Data Analysis Pipeline
RT Retention time
EtOH Ethanol
ADME Absorption, distribution, metabolism, excretion
COX-2 Cyclooxygenase-2
VEGFR2 Vascular endothelial growth factor receptor-2
SW480 Human colorectal adenocarcinoma cell line
T84 Human colorectal carcinoma cell line
RPM Revolutions per minute
HCT Hawkins–Cramer–Truhlar model
MM/GBSA Molecular mechanics/generalized Born surface area
MD Molecular dynamics
GROMACS Groningen Machine for Chemical Simulations
TIP3P Transferable Interaction Potential 3-Point water model
RMSD Root-mean-square deviation
ANOVA Analysis of variance
p53 Tumor protein p53
Caspase-9 Cysteine-aspartic acid protease-9
1-Me-AQ-2-COOH 3,8-Dihydroxy-1-methylanthraquinone-2-carboxylic acid