AAGs	Aging-associated genes
Act1	Nuclear factor kappa B activation agent 1
ADIPOQ	Adiponectin
AGEs	Advanced glycation end products
Akt	Protein Kinase B
Ang II	Angiotensin II
AP-1	Activator protein-1
Atg7	Autophagy-related protein 7
ATR	Ataxia telangiectasia and rad3-related protein
BP	Biological process
CC	Cellular component
cGAS	Cyclic GMP-AMP synthase
Chk1	Checkpoint kinase 1
CRP	C-reactive protein
CTNNβ1	β-Catenin
CXC	Cysteine-x-cysteine chemokines
DL	Drug likeness
ECs	Endothelial cells
ECM	Extracellular matrix
eNOS	Endothelial nitric oxide synthase
EPCs	Endothelial progenitor cells
ERK1/2	Extracellular signal-regulated kinase 1/2
ESR1	Estrogen receptor 1
GEO	Gene Expression Omnibus
GM-CSF	Granulocyte-macrophage colony stimulating factor
GO	Gene Ontology
GRB2	Growth factor receptor-bound protein 2
GSH-Px	Glutathione peroxidase
HERB	High-throughput Experiment- and Reference-guided database of TCM
HIF1α	Hypoxia-inducible factor-1α
HL	Half life
HSP90αA1	Heat shock protein 90 alpha family class A member 1
HUVEC	Human umbilical vein endothelial cell
IGF1	Insulin-like growth factor 1
IGF2	Insulin-like growth factor 2
IGFBP3	Insulin-like growth factor binding protein 3
IL-1β	Interleukin-1β
IL-6	Interleukin-6
IL-8/CXCL8	Interleukin-8
IL-17	Interleukin-17
IL-17R	Interleukin-17 receptor
IRF3	Interferon regulatory factor 3
KEGG	Kyoto Encyclopedia of Genes and Genomes
LASSO	Least absolute shrinkage and selection operator
LC3	Microtubule-associated protein 1 light chain 3
MAPK	Mitogen-activated protein kinase
MCP-1	Monocyte chemoattractant protein-1
MDA	Malondialdehyde
MF	Molecular function
MMPs	Matrix metalloproteinases
MMP-1	Matrix metalloproteinase-1
MMP-2	Matrix metalloproteinase-2
MMP-3	Matrix metalloproteinase-3
MMP-9	Matrix metalloproteinase-9
mTOR	Mammalian target of rapamycin
MYC	Myelocytomatosis oncogene
NCBI	National Center for Biotechnology Information
NFE2L2	Nuclear factor erythroid 2-related factor 2
NF-κB	Nuclear factor-κB
NO	Nitric oxide
OB	Oral bioavailability
PAR1	Protease activated receptor 1
PDGFRβ	Platelet-derived growth factor receptor beta
PECAM1	Platelet endothelial cell adhesion molecule-1
PIK3Cα	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PI3K	Phosphatidylinositol 3 kinase
PPI	Protein–protein interaction
PPARγ	Peroxisome proliferator-activated receptor gamma
PTEN	Phosphate and tension homology deleted on chromosome ten
p21	Cyclin-dependent kinase inhibitor 1A
p53	Tumor protein 53
p62	Sequestosome-1
RAGE	Receptor for advanced glycation end products
Rg	Radius of gyration
RMSD	Root mean square deviation
RMSF	Root mean square fluctuation
ROS	Reactive oxygen species
SASA	Solvent accessible surface area
SIRT1	Silent mating type information regulation 2 homolog 1
SOD	Superoxide dismutase
STRING	Search Tool for the Retrieval of Interacting Genes/Proteins
STING	Stimulator of interferon genes
TCMs	Traditional Chinese Medicines
TCMSP	Traditional Chinese Medicine System Pharmacology Database
Tfh	Follicular helper T cell
TGFβ1	Transforming growth factor β1
Th1	T helper 1 cell
Th17	T helper cell 17
TIMPs	Tissue inhibitors of metalloproteinases
TIMP-1	Tissue inhibitors of metalloproteinase-1
TIMP-3	Tissue inhibitors of metalloproteinase-3
TLR4	Toll-like receptor 4
TNF	Tumor necrosis factor
TNF-α	Tumor necrosis factor-α
TRAF6	TNF receptor-associated factor 6
VAGs	Vascular-associated genes
VSMCs	Vascular smooth muscle cells