Table 2.

Median [minimum, maximum] of constant b in the proportional error model (Eqs. 2 and 4) obtained for methods I–III. First, the model-based error model was used, and the proportionality constants b of diagnostic and therapeutic data were separately fitted. Second, the model-based error model was also used, but a further separation was done: organs and tumours were considered differently, and 4 b-parameters were fitted. Third, the data-based error model was used, and 4 b-parameters (with diagnostic and therapeutic data, organ and tumour separation) were fitted

	Model-based error model (2 bs) Method I		Model-based error model (4 bs) Method II	Data-based Error Model (4 bs) Method III
(8 data)	0.16 [0.02, 0.51]	b D, Organ (5 data)	0.28 [0.09, 0.56]	0.35 [0.13, 1.50]
		b D, Tumor (3 data)	0.36 [0.13, 0.82]	0.27 [0.11, 1.39]
(33 data)	0.28 [0.18, 0.63]	b T, Organ (24 data)	0.31 [0.15, 0.83]	0.16 [0.14, 0.25]
		b T, Tumor (9 data)	0.09 [0.01, 0.25]	0.39 [0.04, 0.80]