Table 2.

Performance in predicting drug indications. Reported is AUPRC

Category	KL	JS	Proximity	DSD	RGCN	HAN	HGT	BioBERT	TxGNN	COMIC
Random	0.50	0.49	0.53	0.49	0.84	0.87	0.72	0.81	0.91	0.9375
Cell proliferation	0.51	0.50	0.47	0.51	0.47	0.65	0.61	0.83	0.92	0.9031
Mental health	0.50	0.50	0.44	0.50	0.55	0.61	0.56	0.64	0.89	0.9046
cardiovascular	0.49	0.50	0.50	0.50	0.41	0.63	0.60	0.66	0.64	0.8817
Anemia	0.47	0.53	0.49	0.51	0.42	0.67	0.53	0.64	0.96	0.9302
Adrenal gland	0.48	0.50	0.48	0.50	0.38	0.59	0.54	0.64	0.99	0.9375
Autoimmune	0.51	0.49	0.56	0.52	0.51	0.53	0.49	0.66	0.87	0.9284
Metabolic disorder	0.51	0.54	0.41	0.51	0.67	0.56	0.54	0.68	0.76	0.9362
Diabetes	0.50	0.52	0.47	0.52	0.40	0.67	0.62	0.69	0.87	0.9114
Neurodegenerative	0.50	0.51	0.49	0.51	0.84	0.71	0.60	0.57	0.95	0.9182